salmon calcitonin (Cibacalcin, Calcimar, Miacalcin)

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Introduction

Salmon calicitonin: Tradenames: Calcimar, Miacalcin. Human calcitonin: Tradename: Cibacalcin.

Indications

Contraindications

Pregnancy category: C 'salmon calcitonin'

Safety in lactation: ? 'salmon calcitonin'

Dosage

Skin test:

  • 1 unit/0.1 mL SC inner aspect of arm (dilution required)
  • observe injection site for 15 minutes for wheal or significant erythema

Injection:

Injection: 200 units/mL SC: tuberculin syringe 1 mL, 26 g, 3/8 inch IM: total volume > 2 mL, syringe 2.5-3 mL, 22 g needle, 1.5 inch

Nasal metered dose:

200 IU/actuation. 2 mL, 14 doses.

Pharmacokinetics

Adverse effects

Mechanism of action

More general terms

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  3. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  4. Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
  5. UCLA Intensive Course in Geriatric Medicine & Board Review, Marina Del Ray, CA, Sept 12-15, 2001
  6. 6.0 6.1 6.2 Physician's First Watch. March 7, 2013 David G. Fairchild, MD, MPH, Editor-in-Chief Massachusetts Medical Society http://www.jwatch.org
    FDA Advisory committee background document. March 5, 2013 http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/ReproductiveHealthDrugsAdvisoryCommittee/UCM341779.pdf
  7. 7.0 7.1 7.2 Overman RA, Borse M, Gourlay ML. Salmon calcitonin use and associated cancer risk. Ann Pharmacother. 2013 Dec;47(12):1675-84. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/24259626