prediction of dementia
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Laboratory
- plasma proteomic profiles predict dementia 10 years in advance[1]
- plasma GFAP, NEFL, GDF15 & LTBP2 consistently associated with dementia
- people with higher plasma GFAP are 2.3 times more likely to develop dementia
- plasma GFAP identified as optimal marker for prediction of dementia
Notes
- there is a dementia risk calculator based on clinical factors
- an MRI score is said to predict dementia[2]
- cardiovascular risk factors are said to predict dementia in CAIDE trial
- there is discussion of predicting dementia in primary care[3]
References
- ↑ 1.0 1.1 Naddaf M Early dementia diagnosis: blood proteins reveal at-risk people. Nature News. 2024 Feb 12 PMID: https://www.ncbi.nlm.nih.gov/pubmed/38347211 https://www.nature.com/articles/d41586-024-00418-9
Guo Y, You J, Zhang Y et al Plasma proteomic profiles predict future dementia in healthy adults. Nature Aging. 2024. Feb 12. PMID: https://www.ncbi.nlm.nih.gov/pubmed/38347190 https://www.nature.com/articles/s43587-023-00565-0 - ↑ 2.0 2.1 Amin Al Olama A et al. Simple MRI score aids prediction of dementia in cerebral small vessel disease. Neurology 2020 Mar 24; 94:e1294. PMID: https://www.ncbi.nlm.nih.gov/pubmed/32123050 https://n.neurology.org/content/94/12/e1294
- ↑ 3.0 3.1 Jongstra S, van Gool WA, Moll van Charante EP et al Improving Prediction of Dementia in Primary Care. Ann Fam Med May/June 2018 vol. 16 no. 3 206-210 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29760023 Free Article <Internet> http://www.annfammed.org/content/16/3/206