tuberculid
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Classification
3 main types of tuberculids
- erythema induratum
- lichen scrofulosorum
- papulonecrotic tuberculid[3]
Pathology
- type-4 hypersensitivity reaction to Mycobacterium tuberculosis
Clinical manifestations
- erythema induratum: localized red-to-violaceous nodules or plaques on posterior calf
- lichen scrofulosorum: many discrete, often monomorphic, 2-4-mm, flat-topped papules, generally on trunk
- papulonecrotic tuberculid: symmetric, recurring eruption of 2-8-mm, firm, inflammatory papules -> pustules becoming necrotic over time, scarring over a period of weeks
- if untreated, may persist for years[3]
Laboratory
- skin biopsy
- acid fast stain generally unrewarding (hypersensitivity)
- mycobacterial cultures also generally unrewarding[3]
More general terms
References
- ↑ Jordaan HF, Schneider JW, Abdulla EA. Nodular tuberculid: a report of four patients. Pediatr Dermatol. 2000 May-Jun;17(3):183-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/10886748
- ↑ Jordaan HF, Schneider JW, Schaaf HS et al Papulonecrotic tuberculid in children. A report of eight patients. Am J Dermatopathol. 1996 Apr;18(2):172-85. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8739993
- ↑ 3.0 3.1 3.2 3.3 Rothaus C A Man with Rash, Abdominal Pain, and Lymphadenopathy. NEJM Resident 360. Jan 16, 2019 https://resident360.nejm.org/content_items/a-man-with-rash-abdominal-pain-and-lymphadenopathy