Mycobacterium chelonae
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Introduction
Not pigmented (non chromagen).
Epidemiology
- causes HIV-associated mycobacterial infection
- environmental source: water, soil
Pathology
- cutaneous lesions
- disseminated multiorgan disease
Laboratory
- rapidly growing in culture
- cultures generally positive in 1 week vs 2-6 weeks
- also see Mycobacterium
Management
- not susceptible to standard anti-tuberculosis drugs
- most strains are susceptible to clarithromycin & amikacin
- other potentially useful agents include: Bactrim, fluoroquinolones, tetracyclines, imipenem, cefoxitin
- minimum of 4 months of therapy