disease interaction(s) of heart disease with depression

Pathology

• stress & depression can provoke detrimental behaviors

Management

• cardiac rehabilitation & exercise can dimimish depression & improve fitness & function
• antidepressant may be indicated
  • SSRI: sertraline & citalopram are 1st line
  • bupropion, mirtazapine & trazodone: less evidence for safety & efficacy in cardiac patients
  • SNRI may increase blood pressure & heart rate
  • tricyclic antidepressants may worsen outcomes
• cognitive behavorial therapy in addition to antidepressant may be better than antidepressant alone

More general terms

• disease interaction