trimethylamine-N-oxide (TMAO)

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Pathology

Comparative biology

More general terms

References

  1. Jump up to: 1.0 1.1 Tang WHW et al. Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk. N Engl J Med 2013 Apr 25; 368:1575 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/23614584 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1109400
    Loscalzo J. Gut microbiota, the genome, and diet in atherogenesis. N Engl J Med 2013 Apr 25; 368:1647. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/23614591 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMe1302154
  2. Jump up to: 2.0 2.1 2.2 2.3 Wang Z, Roberts AB, Buffa JA et al. Non-lethal inhibition of gut microbial trimethylamine production for the treatment of atherosclerosis. Cell 2015 Dec 17; 163:1585 PMID: https://www.ncbi.nlm.nih.gov/pubmed/26687352
  3. Jump up to: 3.0 3.1 3.2 Senthong V, Wang Z, Li XS, Fan Y, Wu Y, Tang WH, Hazen SL. Intestinal Microbiota-Generated Metabolite Trimethylamine-N-Oxide and 5-Year Mortality Risk in Stable Coronary Artery Disease: The Contributory Role of Intestinal Microbiota in a COURAGE- Like Patient Cohort. J Am Heart Assoc. 2016 Jun 10;5(6). PMID: https://www.ncbi.nlm.nih.gov/pubmed/27287696 Free PMC Article
  4. Jump up to: 4.0 4.1 Senthong V, Li XS, Hudec T et al Plasma Trimethylamine N-Oxide, a Gut Microbe-Generated Phosphatidylcholine Metabolite, Is Associated With Atherosclerotic Burden. J Am Coll Cardiol. 2016 Jun 7;67(22):2620-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/27256833
  5. Jump up to: 5.0 5.1 5.2 Senthong V, Wang Z, Li XS, Fan Y, Wu Y, Tang WH, Hazen SL Trimethylamine N-Oxide and Mortality Risk in Patients With Peripheral Artery Disease. J Am Heart Assoc. 2016; 5: e004237, Online October 19, 2016 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27287696 Free PMC Article <Internet> http://jaha.ahajournals.org/content/5/10/e004237.abstract
  6. Jump up to: 6.0 6.1 Kijpaisalratana N, Ament Z, Bevers MB et al Trimethylamine N-Oxide and White Matter Hyperintensity Volume Among Patients With Acute Ischemic Stroke. JAMA Netw Open. 2023;6(8):e2330446. PMID: https://www.ncbi.nlm.nih.gov/pubmed/37610752 PMCID: PMC10448304 Free PMC Article https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2808706
  7. Jump up to: 7.0 7.1 Wang M, Tang WHW, Li X et al The Gut Microbial Metabolite Trimethylamine N-oxide, Incident CKD, and Kidney Function Decline. J Am Soc Nephrol. 2024 Apr 9 PMID: https://www.ncbi.nlm.nih.gov/pubmed/38593157 https://journals.lww.com/jasn/abstract/9900/the_gut_microbial_metabolite_trimethylamine.282.aspx

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