3,3-dimethyl-1-butanol; 3,3-dimethylbutan-1-ol (DMB)
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Function
- inhibits trimethylamine* production by intestinal flora in mice
* trimethyamine is converted into trimethylamine N-oxide (TMAO) by the liver; circulating TMAO levels correlate with atherosclerosis burden in humans[2]
More general terms
References
- ↑ PubChem: 12233
- ↑ 2.0 2.1 Wang Z, Roberts AB, Buffa JA et al. Non-lethal inhibition of gut microbial trimethylamine production for the treatment of atherosclerosis. Cell 2015 Dec 17; 163:1585 PMID: https://www.ncbi.nlm.nih.gov/pubmed/26687352