Borrelia miyamotoi
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Introduction
first identified as a human pathogen in 2011[2]
Epidemiology
- now found in Lyme disease vectors worldwide
- transmitted by the Ixodes scapularis tick in northeastern United States
Pathology
- meningoencephalitis
- found in CSF of older immunocompromised patient with progressive cognitive impairment
- hepatitis
- immunodeficiency/pregnancy may be risk factor
Clinical manifestations
Laboratory
- complete blood count
- liver function tests
- Borrelia miyamotoi serology
- Borrelia burgdorferi serology may be positive
Differential diagnosis
- anaplasmosis
- borreliosis due to Borrelia burgdorferi Managemeent:
- ceftriaxone plus doxycycline (rifampin in pregnancy)
More general terms
References
- ↑ Journal Watch Massachusetts Medical Society Gugliotta JL et al. Meningoencephalitis from Borrelia miyamotoi in an immunocompromised patient. N Engl J Med 2013 Jan 17; 368:240. PMID: https://www.ncbi.nlm.nih.gov/pubmed/23323900
- ↑ 2.0 2.1 2.2 2.3 2.4 Hu LT, Tsibris AM, Branda JA. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 24-2015. A 28-Year-Old Pregnant Woman with Fever, Chills, Headache, and Fatigue. N Engl J Med. 2015 Jul 30;373(5):468-75. PMID: https://www.ncbi.nlm.nih.gov/pubmed/26222563