microtubule-associated protein tau in serum/plasma

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Pathology

* at autopsy

Indications

Reference interval

Clinical significance

Notes

More general terms

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Additional terms

Component of

References

  1. 1.0 1.1 1.2 Shahim P et al Blood Biomarkers for Brain Injury in Concussed Professional Ice Hockey Players. JAMA Neurol. Published online March 13, 2014 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24627036 <Internet> http://archneur.jamanetwork.com/article.aspx?articleid=1846623
    Gatson J and Diaz-Arrastia R Tau as a Biomarker of Concussion JAMA Neurol. Published online March 13, 2014. <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24627000 <Internet> http://archneur.jamanetwork.com/article.aspx?articleid=1846622
  2. 2.0 2.1 Bassett M Plasma Total-Tau Level May Flag CTE - Lack of biomarker frustrates CTE researchers. MedPage Today. April 24, 2017 https://www.medpagetoday.com/MeetingCoverage/AAN/64766
    Alosco M, et al An investigation on repetitive head impact exposure and plasma total tau concentrations in former National Football League players American Academy of Neurology 2017 Annual Meeting
  3. 3.0 3.1 3.2 Pase MP, Beiser AS, Himali JJ et al Assessment of Plasma Total Tau Level as a Predictive Biomarker for Dementia and Related Endophenotypes. JAMA Neurol. Published online March 4, 2019. PMID: https://www.ncbi.nlm.nih.gov/pubmed/30830207 https://jamanetwork.com/journals/jamaneurology/fullarticle/2726948
  4. 4.0 4.1 George J Blood-Based Markers Tied to Brain Cell and Memory Loss. Another step closer to clinical utility for tracking neurodegeneration. MedPage Today April 16, 2021 https://www.medpagetoday.com/meetingcoverage/aan/92140
    Marks J, et al Comparison of neurofilament light and total tau as blood-based biomarkers of neurodegeneration: associations with cognition and neuroimaging outcomes. American Academy of Neurology (AAN) 2021.
  5. 5.0 5.1 5.2 Desai P, Evans D, Dhana K et al Longitudinal Association of Total Tau Concentrations and Physical Activity With Cognitive Decline in a Population Sample. JAMA Netw Open. 2021;4(8):e2120398. Aug 11 PMID: https://www.ncbi.nlm.nih.gov/pubmed/34379124 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2782979
  6. 6.0 6.1 Halloway S et al Serum total tau, neurofilament light, and glial fibrillary acidic protein are associated with mortality in a population study. J Am Geriatr Soc. 2024 Jan;72(1):149-159 PMID: https://www.ncbi.nlm.nih.gov/pubmed/37818793 https://agsjournals.onlinelibrary.wiley.com/doi/full/10.1111/jgs.18632