histone-lysine N-methyltransferase 2B; lysine N-methyltransferase 2B; myeloid/lymphoid or mixed-lineage leukemia protein 4; trithorax homolog 2; WW domain-binding protein 7; WBP-7 (KMT2B, HRX2, KIAA0304, MLL2, MLL4, TRX2, WBP7)

From Aaushi
Jump to navigation Jump to search

Function

S-adenosyl-L-methionine + L-lysine-[[[A137031|histone]]] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[[[A137031|histone]]]

Structure

Compartment

nucleus (putative)

Alternative splicing

named isoforms=2

Expression

Pathology

Notes

  • protein was first named MLL2[2][3]
  • MLL2 corresponds to another protein located on chromosome 12 (see AC O14686). Thus, KMT2B/MLL4 is often referred to as MLL2 & vice versa in the literature

More general terms

Component of

References

Database