disease interaction(s) of diabetes mellitus with dementia
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Introduction
Interactions:
- risk for dementia is increased in patients with diabetes mellitus[1]
- thiazolidines diminish risk for dementia (22%) vs metformin[2]
- sulfonylureas increase risk for dementia (12%) vs metformin[2]
- maintaining hemoglobin A1c within target range diminishes risk of dementia[3]
Notes
see Diabetes-Specific Dementia Risk Score
More general terms
References
- ↑ 1.0 1.1 Exalto LG et al Risk score for prediction of 10 year dementia risk in individuals with type 2 diabetes: a cohort study. The Lancet Diabetes & Endocrinology. August 20,2013 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24622366 <Internet> http://www.thelancet.com/journals/landia/article/PIIS2213-8587(13)70048-2/abstract
- ↑ 2.0 2.1 2.2 Tucker ME One Type of Older Diabetes Drug Cuts Dementia Risk, Another Ups It. Medscape. Oct 11, 2022 https://www.medscape.com/viewarticle/982256
Tang X et al Use of oral diabetes medications and the risk of incident dementia in US veterans aged >= 60 years with type 2 diabetes. BMJ Open Diabetes Research & Care. 2022 10(5): PMID: https://www.ncbi.nlm.nih.gov/pubmed/36220195 PMCID: PMC9472121 Free PMC article https://drc.bmj.com/content/10/5/e002894 - ↑ 3.0 3.1 Underwood PC et al Glycated Hemoglobin A1c Time in Range and Dementia in Older Adults With Diabetes. JAMA Netw Open. 2024;7(8):e2425354 PMID: https://www.ncbi.nlm.nih.gov/pubmed/39093563 PMCID: PMC11297381 Free PMC article. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2821878