hyaluronoglucosaminidase; hyaluronidase (HYAL)

Function

• hydrolysis of hyaluronate
• lowers viscosity of hyaluronate, thus increasing tissue permeability
• random hydrolysis of 1->4-linkages between N-acetyl-beta-D-glucosamine & D-glucuronate residues in hyaluronate

Pharmacology

see Hylenex

More general terms

• glycosidase (glycoside hydrolase)
• lyase

More specific terms

• hyaluronidase PH-20; hyal-PH20; hyaluronoglucosaminidase PH-20; sperm adhesion molecule 1; sperm surface protein PH-20 (SPAM1 HYAL3 PH20)
• hyaluronidase-1; hyal-1; hyaluronoglucosaminidase-1; lung carcinoma protein 1; LuCa-1 (HYAL1, LUCA1)
• hyaluronidase-2; hyal-2; hyaluronoglucosaminidase-2; lung carcinoma protein 2; LuCa-2 (HYAL2, LUCA2)
• hyaluronidase-3; hyal-3; hyaluronoglucosaminidase-3; lung carcinoma protein 3; LuCa-3 (HYAL3, LUCA3)
• hyaluronidase-4 (Hyal-4, Hyaluronoglucosaminidase-4, HYAL4)
• Hylenex (Wydase, Amphadase, Vitrase, Hydase, hyaluronidase)

Additional terms

• hyaluronate; hyaluronic acid; hyaluronan