hyaluronidase-4 (Hyal-4, Hyaluronoglucosaminidase-4, HYAL4)

Function

• endo-hyaluronidase
• degrades hyaluronan to smaller oligosaccharide fragments
• also has chondroitase activity
  • random hydrolysis of 1->4-linkages between N-acetyl-beta-D-glucosamine & D-glucuronate residues in hyaluronate

Structure

belongs to the glycosyl hydrolase 56 family

Compartment

membrane

Expression

detected in placenta & skeletal muscle

More general terms

• hyaluronoglucosaminidase; hyaluronidase (HYAL)
• membrane protein
• glycoprotein

Database

• OMIM: https://mirror.omim.org/entry/604510
• UniProt: http://www.uniprot.org/uniprot/Q2M3T9.html