hydrochlorothiazide/triamterene; HCTZ/triamterene (Dyazide, Maxzide, Maxide)

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Introduction

HCTZ/triamterene 50/75, 25/37.5.

Indications

* minimally lowers blood pressure relative to HCTZ alone (4 mm Hg systolic BP, 1 mm Hg diastolic BP)[4]

Dosage

1/2-1 tab PO QD

Tabs: HCTZ/triamterene 25/37.5, 25/50

Stability: protect from light.

Adverse effects

* see hydrochlorothiazide & triamterene

Drug interactions

see hydrochlorothiazide & triamterene

Laboratory

Mechanism of action

see hydrochlorothiazide & triamterene

More general terms

Components

References

  1. The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
  2. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998 Department of Veterans Affairs, VA National Formulary
  3. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  4. 4.0 4.1 Tu W et al. Triamterene enhances the blood pressure lowering effect of hydrochlorothiazide in patients with hypertension. J Gen Intern Med 2016 Jan; 31:30 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/26194642 <Internet> http://link.springer.com/article/10.1007%2Fs11606-015-3469-1

Database