non-specific esterase stain

Indications

• enzyme cytochemistry staining used in differential diagnosis of hematologic neoplasms

Clinical significance

Positive staining:

• monocytes (inhibited by sodium fluoride),
• AML-M4, M5,
• mature T cells and T-all (cytoplasmic dot),
• carcinomas,
• megaloblastic erythrocytes,
• cytoplasm focally in AML-M7

Negative staining:

• AML-M0, M1, M2, M3,
• ALL (usually)

More general terms

• tissue stain

More specific terms

• microscopic observation in tissue by non-specific esterase stain