AML-M7; acute megakaryoblastic leukemia
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Introduction
AML with > 50% of blasts from megakaryocytic lineage
Epidemiology
- ~3-5% of AML cases
- adults and children
Pathology
- pleomorphic undifferentiated blasts; react with antiplatelet antibodies
- myelofibrosis or increased bone marrow reticulin
Genetics
More general terms
References
- ↑ Cotran et al Robbins Pathologic Basis of Disease, W.B. Saunders Co, Philadelphia, PA 1989 pg 726
- ↑ Mihova D Leukemia - Acute AML not otherwise categorized Acute megakaryoblastic leukemia (AMKL, M7) Pathology Outlines http://www.pathologyoutlines.com/topic/leukemiaM7.html