interleukin-12 receptor

Function

• promotes the proliferation of T-cells as well as NK cells
• induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production

Structure

• low affinity IL-12 receptor IL12RB1 in association with signal-transducting subunit IL12RB2 form high-affinity IL-12 receptor

More general terms

• interleukin receptor
• multisubunit protein

Additional terms

• interleukin-12; cytotoxic lymphocyte maturation factor; NK cell stimulatory factor (IL12, IL-12)