pharmaceutical agents during pregnancy

Management

• depression
  • serotonin-reuptake inhibitors (SSRI)
    • no risk apparent to fetus
  • tricyclic antidepressants
    • nortriptyline (Pamelor)
    • desipramine (Norpramine)
    • monitor levels once each trimester
• bipolar illness
  • lithium carbonate
    • monitor levels monthly
    • monitor levels weekly near delivery
    • fetal ultrasound at 18-20 weeks
      • small risk of fetal heart malformations
• panic disorder
  • prophylaxis
    • Paxil
    • Zoloft
  • acute attacks: Ativan
• obsessive-compulsive disorder
  • serotonin-reuptake inhibitors (SSRI)

* preferred pharmaceutical agents