T-cell surface glycoprotein CD8 beta-2 chain (CD8b pseudogene, CD8BP, CD8B2)

Function

• subunit of CD8
• identifies cytotoxic/suppressor T-cells that interact with MHC class 1 bearing targets
• CD8 is thought to play a role in the process of T-cell mediated killing (putative)

Structure

• contains 1 Ig-like V-type domain (immunoglobulin-like)
• subunit of CD8, a heterodimer of an alpha & a beta chain linked by two disulfide bonds

Compartment

cell membrane; (putative)

Notes

• could be the product of a pseudogene
• gene appears functional but all the mRNAs identified are derived from CD8B/CD8B1

More general terms

• glycoprotein
• membrane protein

Component of

• CD8

Database

• UniProt: http://www.uniprot.org/uniprot/A6NJW9.html