liposarcoma
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Epidemiology
Microscopic pathology
Identification of lipoblasts which range from:
- primitive mesenchymal cells with only tiny lipid droplets
- intermediate form with scanty cytoplasm, multiple variably sized lipid droplets and small nucleus centrally or peripherally located
- signet-ring like cells with most of cytoplasm occupied by single large fat droplet
Histologic subtypes:
- well-differentiated liposarcoma (atypical lipoma/atypical lipomatous tumor)
- lipoma like
- sclerosing
- inflammatory
- spindle cell
- dedifferentiated
- myxoid liposarcoma
- pleomorphic liposarcoma
* histopathology images[4]
Genetics
- implicated genes PRUNE
More general terms
More specific terms
- dedifferentiated liposarcoma
- myxoid liposarcoma
- pleomorphic liposarcoma
- round cell liposarcoma
- well-differentiated liposarcoma; atypical lipomatous tumor; sclerosing liposarcoma; inflammatory liposarcoma; spindle cell liposarcoma
References
- ↑ Enzinger & Weiss. Soft Tissue Tumors. Mosby. 3rd ed. 1995
- ↑ 2.0 2.1 Gebhard et al. Am J Surgical Pathology 26:601-16, 2002
- ↑ DermNet NZ. Lipoma and liposarcoma (images) http://www.dermnetnz.org/lesions/lipoma.html
- ↑ 4.0 4.1 DermNet NZ. Liposarcoma pathology (histopathology images) http://www.dermnetnz.org/pathology/liposarcoma-path.html
- ↑ Schwartz RA, Elston DM (CT image) Medscape: Liposarcoma http://emedicine.medscape.com/article/1102007-overview