dedifferentiated liposarcoma

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Genetics

  • beta-catenin mutations/accumulation are seen in some cases of sclerosing type or dedifferentiated type; these cases tend to have higher MIB-1 labelling[2]

More general terms

References

  1. WHO Classification Tumours of Soft Tissue and Bone Fletcher, Unni & Mertens Eds. IARC Press 2002
  2. 2.0 2.1 Sakamoto A, Oda Y, Adachi T, Saito T, Tamiya S, Iwamoto Y, Tsuneyoshi M. Beta-catenin accumulation and gene mutation in exon 3 in dedifferentiated liposarcoma and malignant fibrous histiocytoma. Arch Pathol Lab Med. 2002 Sep;126(9):1071-8. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12204056