Mycobacterium marinum
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Introduction
Epidemiology
- free-living, does not require host
- disease associated with water exposure, fresh water & salt water
- causes HIV-associated mycobacterial infection
Pathology
- initial lesion is cutaneous granulomatous lesion
- transmitted via lymphatic to joints
- mild, slowly progressive tenosynovitis
- infectious arthritis
- inoculation osteomyelitis
Clinical manifestations
- cutaneous lesions[5] (images)
- inflammatory arthritis localized to the site of the skin lesion
Laboratory
- synovial fluid culture
- also see Mycobacterium
Management
- macrolide, tetracycline, & rifabutin[4]
- moxifloxacin, rifampin, & clarithromycin for 6 months[5]
More general terms
References
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 11,15,16,18. American College of Physicians, Philadelphia 1998,2009, 2012, 2018.
- ↑ Harrison's Principles of Internal Medicine, 13th ed. Isselbacher et al (eds), McGraw-Hill Inc. NY, 1994, pg 722
- ↑ Cheung JP, Fung B, Wong SS, Ip WY. Review article: Mycobacterium marinum infection of the hand and wrist. J Orthop Surg (Hong Kong). 2010 Apr;18(1):98-103. PMID: https://www.ncbi.nlm.nih.gov/pubmed/20427845
- ↑ 4.0 4.1 Aubry A, Chosidow O, Caumes E, Robert J, Cambau E. Sixty-three cases of Mycobacterium marinum infection: clinical features, treatment, and antibiotic susceptibility of causative isolates. Arch Intern Med. 2002 Aug 12-26;162(15):1746-52. PMID: https://www.ncbi.nlm.nih.gov/pubmed/12153378
- ↑ 5.0 5.1 5.2 Su Q, Wang F Images in Clinical Medicine: Painful Nodules on the Arms. N Engl J Med 2021; 384:e41. March 18 PMID: https://www.ncbi.nlm.nih.gov/pubmed/33730457 https://www.nejm.org/doi/full/10.1056/NEJMicm2028530