antithrombotic agent

^[1]^[2]^[3]

Adverse effects

also see anticoagulant & antiplatelet agent
increased risk for subdural hematoma^[1]
- risk is highest for patients on both an antiplatelet agent & warfarin^[1]
complications related to gross hematuria (hospitalization, emergency department visits, & urologic interventions) increased ((124 vs 80 events per 1000 person-years) (RR=2.8)
- complications were more common with anticoagulants than antiplatelet agents
- aspirin with lowest complication rate

↑ ^1.0 ^1.1 ^1.2 Gaist D, Garcia Rodriguez LA, Hellfritzsch M et al Association of Antithrombotic Drug Use With Subdural Hematoma Risk. JAMA. 2017;317(8):836-846. Feb 28, 2017 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28245322 <Internet> http://jamanetwork.com/journals/jama/article-abstract/2605799
↑ Wallis CJ, Juvet T, Lee Y Association Between Use of Antithrombotic Medication and Hematuria-Related Complications. JAMA. 2017;318(13):1260-1271 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28973248 <Internet> http://jamanetwork.com/journals/jama/article-abstract/2656169
↑ Prescriber's Letter 20(5): 2013 Managing Antithrombotics Before Minor Procedures Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=290521&pb=PRL (subscription needed) http://www.prescribersletter.com