cardiac glycoside (digitalis glycoside)

Uses

• digoxin is used clinically as an inotrope & AV node blocking agent

Adverse effects

• acute
  • nausea, vomiting, followed by bradycardia, arrhythmias, hypotension, hyperkalemia, & altered mental status
• chronic
  • anorexia, nausea, vomiting, diarrhea, abdominal pain
  • confusion, drowsiness, disorientation, delirium, headache, hallucinations, seizures
  • photophobia, blurry vision, scotomas, chromatopsia, xanthopsia
• acute & chronic
  • palpitations, chest pressure, dypnea, dizziness, lightheadedness

Management

• digoxin antibody Fab framents (digoxin immune FAB) for suspected cardiac glycoside toxicity

More general terms

• glycoside
• cardiotonic agent

More specific terms

• digitoxin (Crystodigin)
• digoxin (Lanoxin, Lanoxicaps, Digitek)
• ouabain (Strodival)