diflorasone diacetate

Indications

• short-term treatment of inflammation & pruritus secondary to severe steroid-responsive dermatoses
  • allergic dermatitis, atopic dermatitis, contact dermatitis
  • seborrheic dermatitis
• cutaneous T-cell lymphoma
• discoid lupus
• psoriasis
• lichen simplex chronicus
• granuloma annulare

Dosage

Topical: apply 0.05% cream/ointment sparingly BID/TID.

Very high potency (0.05%), (15, 30, 60 g).

Adverse effects

• uncommon (< 1%)
  • burning, itching, irritation, dryness, folliculitis, hypertrichosis, acne, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin maceration, secondary infection, skin atrophy, striae, miliaria

• drug adverse effects of glucocorticoids
• drug adverse effects of immunosuppressive agents

More general terms

• glucocorticoid
• antipruritic agent

More specific terms

• Diflorasone Topical (Psorcon, Florone, Maxiflor)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3056
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=71414
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=71415