lodoxamide (Alomide)

Introduction

Tradenames: Alomide.

Indications

• treatment of vernal keratoconjunctivitis, vernal conjunctivitis, & vernal keratitis

Contraindications

Caution: NOT for use in patients wearing soft contact lenses

pregnancy category = b

safety in lactation = ?

Dosage

• adults & children > 2 years of age:
  • 1-2 drops QID for up to 3 months

Solution: 0.1% (10 mL)

Adverse effects

• common (> 10%)
  • transient burning, stinging, discomfort
• less common (1-10%)
  • blurred vision, corneal erosion/ulcer, eye pain, corneal abrasion, headache
• uncommon (< 1%)
  • dizziness, somnolence, rash, nausea, stomach discomfort, blepharitis, sneezing, dry nose
• other
  • crystalline deposits

Mechanism of action

• mast-cell stabilizer that inhibits type-1 immediate hypersentivity reaction

More general terms

• ocular decongestant

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=44563