thiotepa; thiophosphamide (Tespa, Thioplex)

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Introduction

Tradenames: Tespa, Thioplex.

Indications

Contraindications

pregnancy category = d

Dosage

Powder for injection: 15 mg. (1 mg/mL is isotonic)

Pharmacokinetics

elimination via liver

1/2life = 2-3 hours

Adverse effects

Drug interactions

Test interactions

increases serum K+

Mechanism of action

More general terms

References

  1. Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998
  2. Kaiser Permanente Northern California Regional Drug Formulary, 1998
  3. Deprecated Reference

Database