pipecuronium (Arduan)

From Aaushi
Jump to navigation Jump to search

Introduction

Tradename: Arduan.

Indications

Contraindications

Caution:

Dosage

  • adults:
    • initial: 85-100 ug/kg IV
    • maintenance: 5-25 ug/kg
  • children 1-14 years of age may be less sensitive to effects
  • infants 3 months to 1 year: adult schedule

Powder for injection: 10 mg vial.

Pharmacokinetics

  • onset of action: within 2-3 minutes
  • metabolized in the liver primarily to 3 desacetyl- pipecuronium
  • elimination: 40% excreted unchanged in the urine

elimination via liver

elimination via kidney

Adverse effects

More general terms

References

  1. Kaiser Permanente Northern California Regional Drug Formulary, 1998

Database