nabilone (Cesamet)

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Introduction

Tradename: Cesamet, DEA-controlled substance: class 2

Indications

* see psychosis & agitation in the elderly

Pregnancy category C

Dosage

1-2 mg PO BID-TID

Tabs: 1 mg (bottles of 20)

Adverse effects

Drug interactions

Mechanism of action

More general terms

References

  1. Prescriber's Letter 13(8): 2006 New Drug: Cesamet (Nabilone) Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=220813&pb=PRL (subscription needed) http://www.prescribersletter.com
  2. 2.0 2.1 Monaco K Nabilone Effective for Easing Agitation in Alzheimer's - Cognition, neuropsychiatric symptoms also improved with synthetic cannabinoid. MedPage Today. July 25, 2018 https://www.medpagetoday.com/meetingcoverage/aaic/74214
    Lanctot K, et al Nabilone significantly improves agitation/aggression in patients with moderate-to-severe AD: Preliminary results of a placebo- controlled, double-blind, cross-over trial. Alzheimer's Association International Conference (AAIC) 2018; Abstract F4-02-04.
  3. 3.0 3.1 Peball M, Krismer F, Knaus HG et al. Non-motor symptoms in Parkinson's disease are reduced by nabilone. Ann Neurol 2020 Aug 5; [e-pub] PMID: https://www.ncbi.nlm.nih.gov/pubmed/32757413 https://onlinelibrary.wiley.com/doi/10.1002/ana.25864
  4. Valeant Pharmaceuticals International http://www.valeant.com

Database