gonadal steroid biosynthesis

Biochemistry

• steroid biosynthesis 14
  • enzyme: 17-hydroxysteroid dehydrogenase
  • substrate: androstenedione + NADPH
  • product: testosterone + NADP
• steroid biosynthesis 15
  • enzyme: aromatase
  • substrate:((testosterone + O2 + NADPH
  • product: estradiol + NADP
• steroid biosynthesis 16
  • enzyme: aromatase
  • substrate: androstenedione + O2 + NADPH
  • product: estrone + NADP
• steroid biosynthesis 17
  • enzyme: 17-hydroxysteroid dehydrogenase
  • substrate: estradiol + NADP
  • product: estrone + NADPH
• steroid biosynthesis 18
  • enzyme: 17-hydroxysteroid dehydrogenase
  • substrate: dehydroepiandrosterone + NADPH
  • product: androstenediol + NADP
• steroid biosynthesis 19
  • enzyme: 3-hydroxysteroid dehydrogenase
  • substrate: androstenediol + NADP
  • product: testosterone + NADPH

* see figure

More general terms

• steroid biosynthesis

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?