17-hydroxysteroid dehydrogenase or 17-beta keto steroid dehydrogenase

Function

• converts androstenedione to testosterone & estrone to estradiol
• this is the only reversible enzyme system involved in steroid biosynthesis

Notes

• may be 2 different enzymes under different control, one localized to testes

More general terms

• hydroxysteroid dehydrogenase

More specific terms

• 17 beta-hydroxysteroid dehydrogenase (estradiol 17 beta-dehydrogenase, HSD17B1)

Additional terms

• gonadal steroid biosynthesis