splenic marginal zone B-cell lymphoma

^[1]^[2]^[3]

Introduction

B cell neoplasm of small lymphocytes which surround and replace splenic white pulp germinal centers, efface follicle mantle and merge with marginal zone of larger cells.

working formulation category/Lukes-Collins: small lymphocytic lymphoma Rappaport: well differentiated lymphocytic lymphoma

↑ Harris NL, Jaffe ES, Stein H, Banks PM, Chan JK, Cleary ML, Delsol G, De Wolf-Peeters C, Falini B, Gatter KC, et al. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood. 1994 Sep 1;84(5):1361-92. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/8068936
↑ Chan JK, Banks PM, Cleary ML, Delsol G, De Wolf-Peeters C, Falini B, Gatter KC, Grogan TM, Harris NL, Isaacson PG, et al. A revised European-American classification of lymphoid neoplasms proposed by the International Lymphoma Study Group. A summary version. Am J Clin Pathol. 1995 May;103(5):543-60. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7741099
↑ WHO Classification Tumours of Haematopoietic and Lymphoid Tissues. IARC Press 2001.