Fanconi anemia complementation group complex (FA complex)

Function

• complex formed by Fanconi anemia complementation group proteins
• DNA repair protein
• postreplication repair
• cell cycle checkpoint function
• interstrand DNA cross-link repair
• maintenance of normal chromosome stability
• hematopoiesis
• interacts with FANCD2
• see Fanconi anemia

Structure

• subunits: PHF9, FANCA, FANCC, FANCE, FANCF, FANCG, FANCM

Pathology

• complex in not found in patients with Fanconi anemia

More general terms

• molecular complex
• nuclear protein

Additional terms

• Fanconi anemia
• Fanconi anemia group D2 protein; protein FACD2 (FANCD2, FACD)