Fanconi anemia group F protein; protein FACF (FANCF)

Function

• DNA repair protein
• postreplication repair
• cell cycle checkpoint function
• interstrand DNA cross-link repair
• maintenance of normal chromosome stability
• component of FA complex

Compartment

nucleus

Pathology

• defects in FANCF are a cause of Fanconi anemia

More general terms

• nuclear protein
• protein subunit

Additional terms

• Fanconi anemia

Component of

• Fanconi anemia complementation group complex (FA complex)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2188
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2188
• OMIM: https://mirror.omim.org/entry/227650
• OMIM: https://mirror.omim.org/entry/603467
• UniProt: http://www.uniprot.org/uniprot/Q9NPI8.html