MHC class II antigen (HLA-DR, HLA-DP, HLA-DQ)

Classification

includes HLA-DR, DQ & DP molecules

Function

• recognized in association with antigen by CD4/TCR

Expression

• present on monocytes, macrophages & dendritic cells
• can be induced in endothelial cells, renal tubular epithelial cells & fibroblasts by interferon

More general terms

• major histocompatibility complex [MHC] antigen
• glycoprotein
• multisubunit protein