T cell receptor

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Introduction

Associates with CD3 in TcR/CD3 complex; in < 10% of T-cells, the TCR is formed by TCR-delta/TCR-gamma heterodimer. It is also associated with at least 2 src family tyrosine kinases, p59fyn & ZAP-70[3]

More general terms

Additional terms

References

  1. Springer TA. Adhesion receptors of the immune system. Nature. 1990 Aug 2;346(6283):425-34. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1974032
  2. Altman A, Coggeshall KM, Mustelin T. Molecular events mediating T cell activation. Adv Immunol. 1990;48:227-360. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1693465
  3. 3.0 3.1 Migita K, Eguchi K, Kawabe Y, Nagataki S. Tyrosine phosphorylation participates in peripheral T-cell activation and programmed cell death in vivo. Immunology. 1995 Aug;85(4):550-5. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7558148