transforming growth factor beta-2; TGF-beta-2; BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; polyergin (TGFB2)
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Function
- suppressive effects on interleukin-2 dependent T-cell growth
- interacts with ASPN
Structure
- homodimer, disulfide-linked
- belongs to the TGF-beta family
Compartment
Alternative splicing
named isoforms=2; A, B
Pathology
- chromosomal translocation t(1;7)(q41;p21) involving TGFB2 is with HDAC9 is found in a family with Peters anomaly
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/P61812.html
- ↑ NIEHS-SNPs http://egp.gs.washington.edu/data/tgfb2/
- ↑ Wikipedia; Note: TGF beta-2 entry http://en.wikipedia.org/wiki/TGF_beta_2
- ↑ Sporn MB, Roberts AB. Interactions of retinoids and transforming growth factor-beta in regulation of cell differentiation and proliferation. Mol Endocrinol. 1991 Jan;5(1):3-7. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2017191
- ↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7042