Peters anomaly

Pathology

• central corneal leukoma
• absence of the posterior corneal stroma & Descemet membrane
• variable degree of iris & lenticular attachments to central- posterior cornea

Genetics

• associated with defects in CYP1B1
• associated with defects in FOXC1
• associated with defects in PAX6
• chromosomal translocation t(1;7)(q41;p21) involving HDAC9 with TGFB2 is found in a family with Peters anomaly

More general terms

• congenital anomaly (birth defect)
• genetic disease of the eye

Database

• OMIM: https://mirror.omim.org/entry/604229