phospholipase-D (PLD)
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Function
- hydrolyzes phosphatidylcholine to phosphatadic acid + choline
- may be activated by ceramide[3]
More general terms
More specific terms
- inactive phospholipase D5 (inactive PLD 5, inactive choline phosphatase 5, inactive phosphatidylcholine-hydrolyzing phospholipase D5, PLDc, PLD5)
- N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (NAPE-hydrolyzing phospholipase D, NAPE-PLD, NAPEPLD, C7orf18)
- phosphatidylinositol [PI] glycan-specific phospholipase D1 (glycoprotein phospholipase D1, glycosyl-phosphatidylinositol specific phospholipase D1, GPLD1, PIGPLD1)
- phosphatidylinositol [PI] glycan-specific phospholipase D2 (glycoprotein phospholipase D2, glycosyl-phosphatidylinositol specific phospholipase D2, GPLD2)
- phospholipase D family member FLJ33580 (PLD6)
- phospholipase D3 (PLD 3, choline phosphatase 3, phosphatidylcholine-hydrolyzing phospholipase D3, HindIII K4L homolog, Hu-K4, PLD3)
- phospholipase D4 (PLD 4, choline phosphatase 4, phosphatidylcholine-hydrolyzing phospholipase D4, PLD4, C14orf175, UNQ2488/PRO5775)
- phospholipase-D1 (PLD1, choline phosphatase 1, phosphatidylcholine-hydrolyzing phospholipase D1, hPLD1)
- phospholipase-D2, choline phosphatase 2 (phosphatidylcholine-hydrolyzing phospholipase D2, hPLD2, PLD1C, PLD2)
Additional terms
References
- ↑ Dennis EA, Rhee SG, Billah MM, Hannun YA. Role of phospholipase in generating lipid second messengers in signal transduction. FASEB J. 1991 Apr;5(7):2068-77. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1901288
- ↑ Liscovitch M. Crosstalk among multiple signal-activated phospholipases. Trends Biochem Sci. 1992 Oct;17(10):393-9. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1455508
- ↑ 3.0 3.1 Hannun YA, Obeid LM. Ceramide: an intracellular signal for apoptosis. Trends Biochem Sci. 1995 Feb;20(2):73-7. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/7701566
- ↑ Wikipedia, hospholipase D entry http://en.wikipedia.org/wiki/phospholipase_D