CD86, activation B7-2 antigen, B70, fun-1 or BU63

Function

• involved in costimulatory signal for interleukin 2 production & T lymphocyte proliferation
• ligand for CD28, CD152

Expression

• dendritic cells
• Langerhans cells
• memory B cells
• germinal center B cells, centrocytes > centroblasts
• monocytes, low levels
• activated T cells
• endothelial cells

More general terms

• CD antigen
• glycoprotein
• immunoglobulin superfamily protein
• receptor

Database

• UniProt: http://www.uniprot.org/uniprot/P42081.html
• OMIM: https://mirror.omim.org/entry/601020
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=942