ras GTPase activator protein (Ras p21 protein activator, p120, rasGAP, RASA1)

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Introduction

Facilitates p21ras GTPase activity.

Function

Structure

Compartment

Alternative splicing

named isoforms=2

Pathology

More general terms

More specific terms

Additional terms

References

  1. Kazlauskas A, Ellis C, Pawson T, Cooper JA. Binding of GAP to activated PDGF receptors. Science. 1990 Mar 30;247(4950):1578-81. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2157284
  2. Ellis C, Moran M, McCormick F, Pawson T. Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases. Nature. 1990 Jan 25;343(6256):377-81. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1689011
  3. Matsuda M, Mayer BJ, Fukui Y, Hanafusa H. Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins. Science. 1990 Jun 22;248(4962):1537-9. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1694307
  4. Wigler MH. Oncoproteins. GAPs in understanding Ras. Nature. 1990 Aug 23;346(6286):696-7. PMID: https://www.ncbi.nlm.nih.gov/pubmed/2201920
  5. Liscovitch M. Crosstalk among multiple signal-activated phospholipases. Trends Biochem Sci. 1992 Oct;17(10):393-9. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1455508
  6. 6.0 6.1 6.2 Boguski MS & McCormick F Proteins regulating Ras and its relative. Nature 366:643 1993 PMID: https://www.ncbi.nlm.nih.gov/pubmed/8259209
  7. GeneReviews https://www.genecards.org/cgi-bin/carddisp.pl?gene=RASA1
  8. UniProt http://www.uniprot.org/uniprot/P20936.html

Database