Ras GTPase-activating protein 3; GAP1(IP4BP); ins P4-binding protein (RASA3)

Function

• inhibitory regulator of the Ras-cyclic AMP pathway
• binds inositol tetrakisphosphate (IP4) with high affinity
• might be a specific IP4 receptor

Structure

• contains 1 Btk-type Zn+2 finger
• contains 2 C2 domains
• contains 1 PH domain
• contains 1 Ras-GAP domain

Compartment

cell membrane

More general terms

• ras GTPase activator protein
• zinc finger protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=22821
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:22821
• OMIM: https://mirror.omim.org/entry/605182
• UniProt: http://www.uniprot.org/uniprot/Q14644.html