transcription factor ETV7; transcription factor Tel-2; ETS-related protein Tel2; Tel-related Ets factor (ETV7, TEL2, TELB, TREF)

Function

• transcriptional repressor
• binds to the DNA sequence 5'-CCGGAAGT-3'

Structure

• belongs to the ETS family
• contains 1 ETS DNA-binding domain
• contains 1 PNT (pointed) domain

Compartment

nucleus

Alternative splicing

• named isoforms=8; A-H
• isoform A & isoform C do not seem to have repressor activity

Expression

• expressed in hematopoietic tissues

More general terms

• Ets family protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51513
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51513
• OMIM: https://mirror.omim.org/entry/605255
• UniProt: http://www.uniprot.org/uniprot/Q9Y603.html