ETS DNA-binding domain

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Introduction

A conserved domain of about 85-90 amino acid residues, found in ets family proteins. It is rich in aromatic & positively charged amino acid residues & is involved in DNA-binding (purine-rich). The ETS domain is the human homolog of the drosophila protein E74A.

More general terms

References

  1. ↑ Macleod K, Leprince D, Stehelin D. The ets gene family. Trends Biochem Sci. 1992 Jul;17(7):251-6. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1502727
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