S100 Ca+2-binding protein
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Structure
- occurs as dimer of two alpha, two beta or one alpha & one beta subunit(s)
Compartment
Expression
Pathology
- found in:
- melanoma
- clear cell sarcoma
- gliomas
- peripheral nerve sheath tumors
- chordoma
- Langerhans cell lesions
- chondrosarcoma
- liposarcoma - lipoblasts
- GIST: 10-20% +
- gastric adenocarcinoma: 20% +, < 25% of cells
- granular cell tumors
Laboratory
widely used for immunohistochemistry analyses
More general terms
Additional terms
References
- ↑ Dabbs. Diagnostic Immunohistochemistry. Churchill Livingstone. 2002