protein S100-P; S100 Ca+2-binding protein P (S100P S100E)

Function

• interacts with S100PBP & S100Z
• binds 2 Ca+2

Structure

• homodimer
• belongs to the S-100 family
• contains 2 EF-hand domains

Compartment

• nucleus, cytoplasm
• colocalizes with S100PBP in the nucleus

Pathology

• up-regulated in various pancreatic ductal adenocarcinomas & pancreatic intraepithelial neoplasias

More general terms

• protein subunit
• placental protein

Additional terms

• S100 Ca+2-binding protein

Database

• UniProt: http://www.uniprot.org/uniprot/P25815.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6286
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6286
• OMIM: https://mirror.omim.org/entry/600614