lysosome-associated membrane glycoprotein 3; lysosomal-associated membrane protein 3; LAMP-3; DC-lysosome-associated membrane glycoprotein; DC LAMP; protein TSC403; CD208 (LAMP3, DCLAMP, TSC403)

Function

• might change the lysosome function after the transfer of peptide-MHC class 2 molecules to the surface of dendritic cells

Structure

belongs to the LAMP family

Compartment

• lysosome membrane

Expression

• expressed in lymphoid organs & dendritic cells
• expressed in lung

Pathology

• up-regulated in carcinomas including:
  • esophageal carcinoma
  • colorectal carcinoma
  • ureteral carcinoma
  • gastric carcinoma
  • breast carcinoma
  • fallopian tube carcinoma
  • thyroid carcinoma
  • parotid carcinoma

More general terms

• CD antigen
• lysosome-associated membrane glycoprotein (LAMP)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=27074
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:27074
• OMIM: https://mirror.omim.org/entry/605883
• UniProt: http://www.uniprot.org/uniprot/Q9UQV4.html