tropomyosin receptor kinase (trk) proto-oncogene protein (NTRK)

From Aaushi
Jump to navigation Jump to search

Pharmacology

* NTRK gene-fusions are rare, but found in many tumor types[2]

More general terms

More specific terms

References

  1. 1.0 1.1 Drilon A, Laetsch TW, Kummar S et al Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children. N Engl J Med 2018; 378:731-739. February 22, 2018 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/29466156 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1714448
  2. 2.0 2.1 Alexander Otto M FDA Expands Repotrectinib Label to All NTRK Gene Fusion+ Solid Tumors. Medscape. June 13, 2024 https://www.medscape.com/viewarticle/fda-expands-repotrectinib-label-all-ntrk-gene-fusion-solid-2024a1000b3q