NET proto-oncogene protein; ETS domain-containing protein Elk-3; ETS-related protein NET; ETS-related protein ERP; SRF accessory protein 2; SAP-2 (ELK3, NET, SAP2)

Function

• may be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or mos
• forms a ternary complex with the serum response factor & the ETS & SRF motifs of the Fos serum response element
• interacts with CTBP1

Structure

• belongs to the ETS family
• contains 1 ETS DNA-binding domain

Compartment

nucleus

More general terms

• Ets family protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2004
• OMIM: https://mirror.omim.org/entry/600247
• UniProt: http://www.uniprot.org/uniprot/P41970.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2004