leucine-rich repeat & fibronectin type III domain-containing protein 1 (synaptic adhesion-like molecule 2, LRFN1, KIAA1484, SALM2)

Function

• role in the regulation of excitatory synapses
• interacts with DLG1, DLGAP1, AMPA receptors & NMDA receptors (putative)
• interacts with DLG4
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• glycosylated (putative)
• belongs to the LRFN family
• contains 1 fibronectin F3 module
• contains 1 Ig-like (immunoglobulin-like) domain
• contains 7 LRR repeats (leucine-rich repeats)

Compartment

membrane, cell junction, synapse (putative)

More general terms

• glycoprotein
• membrane protein
• phosphoprotein
• leucine-rich repeat-containing protein (LRRC)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9P244.html